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A study monitor from the sponsor supervised that the study was conducted according to the study protocolthe Good Clinical Practice and the Mexican national regulation.
Norfloxacin is given to treat urinary tract infectionssuch as cystitis and chronic prostatitisIt works by killing the bacteria which are the cause of the infection.
This is not a list of all drugs or health problems that interact with Noroxinnorfloxacin
Twenty-six healthy male subjects were randomized to study sequencesAs drug absorption results from numerous intricate processesall susceptible to show sex differenceDrugs are mostly absorbed in the proximal intestinenorfloxacinand thus their disposition is sensitive to gastric emptying time and small intestine motilityThere are reports showing that gastric motility is partially controlled by sex hormonesThe gastric emptying time is usually shorter in women than in men and does vary during pregnancy and the cycle menstrualWomen were not included in the study to reduce the intersubject plasma concentration variability13,14Mexican regulation does not require strictly participation of female subjects or fed studies for this type of research.
To control the effects of food on drug bioavailabilitydiet was standardizedand meals were planned by a nutritionist and similar in schedulequantity and ingredients for all study subjects during the internment periodThe first day of each study periodDay-1a dinner
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